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傳統(tǒng)上認為，肥胖是人體攝入高熱量食物與能量消耗對比的結(jié)果。 最新發(fā)表在《環(huán)境污染》雜志上的醫(yī)學(xué)研究表明：一些持久性有機污染物的累計水平程度與個人的肥胖、血清膽固醇和甘油三酯有關(guān)，不論性別、年齡、居住地或者吸煙情況。  這篇研究分析了近300名男性和女性脂肪組織中的污染物積累程度。通過物質(zhì)的分析，這些污染物被稱為有機持久性污染物，可以在環(huán)境中保存多年，甚至幾十年也不會退化掉。人類主要通過飲食暴露于這些污染物中，持久性的有機污染物在人體的脂肪中逐漸積累。 此次研究中，持久性有機污染物分析包括： DDE，殺蟲劑DDT的主要代謝物，在1980年代被廣泛的使用，目前DDE被一些國家用來對抗瘧疾。 殺蟲劑林丹，在過去經(jīng)常用在農(nóng)業(yè)當(dāng)中，治療虱子和疥瘡。 多氯聯(lián)苯，用于許多工業(yè)設(shè)備，以及一些仍然存在的舊變壓器當(dāng)中。  所有的這些污染物都與肥胖的指標(biāo)相關(guān)，以及與膽固醇或甘油三酯的水平相關(guān)。研究員Arrebola博士表示：“有機污染物積累水平較高的人群定量為更肥胖人群，同時他們也呈現(xiàn)出較高水平的膽固醇和甘油三酯，這些都被視為重要的心血管疾病的危險因素。盡管這些關(guān)系是復(fù)雜的，它們也并不是總呈現(xiàn)為線性模式?！?br/> 英文原文： Level of pollutants accumulated in the body linked to obesity levels This is a study published in the journal Environmental Pollution, included researchers from the University of Granada, the San Cecilio and Virgen de las Nieves university hospitals, and the Andalusian School of Public Health, all of them members of the Granada Biohealth Research Institute. This research has analysed the levels of pollutants accumulated in adipose tissue (fat) in nearly 300 men and women, who were attended in the surgery services of two hospitals in the province of Granada (Spain). The substances analysed, known as persistent organic pollutants (POPs), can remain in the environment for years, even decades, without degrading. 'Humans are exposed to POPs mainly through diet. Besides, POPs accumulate gradually in body fat, and this is the reason why the median levels in our study give us an idea of an individual's accumulated exposition over a number of years,' says Juan Pedro Arrebola, the main author of the article. Using complex statistical methods, these scientists confirmed that the accumulated levels of several POPs were related to obesity and to serum levels of cholesterol and triglycerides in individuals, irrespective of the gender, age, place of residence or smoking habits of participants in the survey. 'In general we found that people with higher levels of POPs were quantitatively more obese, and also showed higher levels of cholesterol and triglycerides, all of them regarded as important risk factors for cardiovascular disease, although these relations were complex and they did not always show linear patterns,' Arrebola claims. POPs subject to analysis Those POPs subject to analysis include DDE, the main metabolite of pesticide DDT, widely used all over the world in the 1980s, and currently employed by some countries to combat malaria. They also included the insecticide lindane, frequently used in the past in agriculture and also in certain medicines for lice and scabies. The survey also included a group of polychlorinated biphenyls or PCBs, used in numerous industrial equipment, and which are still present in old electric transformers. All these pollutants were somehow associated with obesity indexes, as well as cholesterol and/or triglycerides levels. In spite of the fact that their use is currently very restricted, POPs are a very serious public health problem. Actually, 100% of participants in this survey presented detectable levels of one or more of these compounds. 'This universal [exposure] turns their impact on human health into a most important issue. Besides, our results suggest that there are no safe exposure levels for these pollutants, which can also interact among them to affect health,' Arrebola added. Previous studies have demonstrated that the general population is exposed to POPs mainly through food with a high fat content. This includes fish and meat from large animals with a high level of fat. This is the reason why a growing number of researchers recommend against over-consumption. Doctor Arrebola's research group is currently monitoring the subjects of their study over the course of several years, to confirm whether those subjects exposed have shown a higher risk of developing certain pathologies, such as high blood pressure, obesity, or cardiovascular disease. 'Obesity-genic' Pollutants Obesity has become a universal epidemic whose impact in Europe has tripled during the last few decades. The most important problem is that obese people have a high risk of suffering from numerous health problems such as cardiovascular disease, which the World Health Organisation considers the main cause of death worldwide. It has been traditionally thought that obesity results from a high caloric intake in comparison with energy expenditure. 'We believe that the results are not just the consequence of a higher intake of food by obese people. There is evidence that human exposure to certain chemical substances called 'obesogenic' could favour the growth and proliferation of adipocytes (fat cells), and provoke therefore an increase in body fat. We suspect besides that certain environmental pollutants could also provoke alterations in cholesterol and triglycerides levels and therefore contribute to the development of cardiovascular disease,' Arrebola concludes. |
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來自： 中國健康食品網(wǎng) > 《待分》
