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      《自然》發(fā)布:肝癌重大突破!拉斯克獎(jiǎng)專(zhuān)家即將突破肝癌治療瓶頸~

       莫言今日無(wú)知己 2018-03-24

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      [4] Kenerson, H. L. et al. Akt and mTORC1 have di?erent roles during liver tumorigenesis in mice. Gastroenterology 144, 1055–1065 (2013).

      [5] Guri, Y. et al. mTORC2 promotes tumorigenesis via lipid synthesis. Cancer Cell 32, 807–823 (2017).

      [6] Makowska, Z. et al. Gene expression analysis of biopsy samples reveals critical limitations of transcriptome-based molecular classifcations of hepatocellular carcinoma. J. Pathol. Clin. Res. 2, 80–92 (2016).

      [7] Vogelstein, B. et al. Cancer genome landscapes. Science 339, 1546–1558(2013).

      [8] Vijayakrishnan, J. et al. A genome-wide association study identifes risk loci for childhood acute lymphoblastic leukemia at 10q26.13 and 12q23.1. Leukemia 31, 573–579 (2017).

      [9] Lesseur, C. et al. Genome-wide association analyses identify new susceptibility loci for oral cavity and pharyngeal cancer. Nat. Genet. 48, 1544–1550 (2016).




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