圣誕節(jié)了,不允許我們的忠(Yi)實(shí)(Shi)讀(Fu)者(Mu)收不到禮物,特獻(xiàn)上12張與癌癥免疫療法相關(guān)的干貨圖片。 圖①:γδ T細(xì)胞的抗腫瘤生物學(xué) 圖片來源:Nat. Rev. Cancer [1] ![]() ![]() ![]() Cancer-Immunotherapy-2020-Calendar封面圖 | 上圖顯示了形成腫瘤免疫環(huán)境的適應(yīng)性和先天免疫系統(tǒng)的多種免疫細(xì)胞類型。下圖顯示了癌癥免疫循環(huán)的連續(xù)步驟:抗原生成→樹突狀細(xì)胞向T細(xì)胞呈遞抗原→啟動(dòng)和激活針對(duì)癌癥特異性抗原的效應(yīng)T細(xì)胞反應(yīng)→T細(xì)胞進(jìn)入腫瘤部位,識(shí)別并殺死癌細(xì)胞(圖片來源:Nat. Rev. Genet. [6]) ——2月4日,世界癌癥日(World Cancer Day) ——2月15日,國際兒童癌癥日(International Childhood Cancer Day) ——4月7日,世界衛(wèi)生日(World Health Day) ——4月24-29日,AACR年會(huì) ——4月29日,世界免疫學(xué)日(World Immunology Day) ——5月8日,世界卵巢癌日(World Ovarian Cancer Day) ——5月28日,世界血癌日(World Blood Cancer Day) ——5月29日-6月2日,ASCO年會(huì) ——6月8日,世界腦腫瘤日(World Brain Tumour Day) ——9月14-17日,國際癌癥免疫療法會(huì)議(International Cancer lmmunotherapy Conference) ——9月18-22日,ESMO年會(huì) ——11月10-14日,癌癥免疫療法學(xué)會(huì)(SITC)年會(huì) ——11月21日,世界胰腺癌日(World Pancreatic Cancer Day) 后臺(tái)回復(fù)免疫療法可下載完整日歷。 最后,祝所有讀者,節(jié)日快樂,2020年,一切順心。 相關(guān)論文: [1] Silva-Santos, B. et al. γδ T cells: pleiotropic immune effectors with therapeutic potentialin cancer. Nat. Rev. Cancer 19, 392–404 (2019). [2] Jones, D. T. W. et al. Molecular characteristics and therapeutic vulnerabilities across paediatric solid tumours. Nat. Rev. Cancer 19, 420–438 (2019). [3] Li, X. et al. Navigating metaboliccpathways to enhance antitumour immunity and immunotherapy. Nat. Rev. Clin. Oncol. 16, 425–441 (2019). [4] Galon, J. & Bruni , D. Approachesto treat immune hot, altered and cold tumours with combination immunotherapies. Nat. Rev. Drug Discov. 18, 197–218 (2019). [5] Lim, M. et al. Current state of immunotherapy for glioblastoma. Nat. Rev. Clin. Oncol. 15, 422–442 (2018). [6] Hackl, H. et al. Computational genomics tools for dissecting tumour–immunecell interactions. Nat. Rev. Genet. 17, 441–458 (2016). [7] O’Donnell, J. S. et al. Cancer immunoediting and resistance to T cell-based immunotherapy. Nat. Rev. Clin. Oncol. 16, 151–167 (2019). [8] Sanli, O. et al. Bladder cancer. Nat. Rev. Disease Primers 3, 17022 (2017). [9] Riley, R. S., June, C. H., Langer, R.& Mitchell , M. J. Delivery technologies for cancer immunotherapy. Nat.Rev. Drug Discov. 18, 175–196 (2019). [10] Harrington, K. et al. Optimizing oncolytic virotherapy in cancer treatment. Nat. Rev. Drug Discov. 18, 689–706 (2019). [11] Feigal, E. G. et al. At the end of the beginning:immunotherapies as living drugs. Nat. Immunology 20, 955–962 (2019). 參考資料: 1# Cancer-Immunotherapy-2020-calendar(來源:Nature Reviews Clinical Oncology) 2# 35th Anniversary Annual Meeting & Pre-Conference Programs (SITC 2020)(來源:Society for Immunotherapy of Cancer) 3# 2020 International Cancer Immunotherapy Conference(來源:International Cancer lmmunotherapy Conference) 4# 56th Annual Meeting of the American Society Of Clinical Oncology(來源:ASCO Annual Meeting) |
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